How dangerous is a coronavirus infection?
Usually coronavirus illnesses are fairly mild, affecting just the upper airway. But the new virus, as well as both SARS and MERS, are different.
Those three types of betacoronaviruses can latch onto proteins studding the outside of lung cells, and penetrate much deeper into the airway than cold-causing coronaviruses, says Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases in Bethesda, M.D. The 2019 version is “a disease that causes more lung disease than sniffles,” Fauci says.
Damage to the lungs can make the viruses deadly. In 2003 and 2004, SARS killed nearly 10 percent of the 8,096 people in 29 countries who fell ill. A total of 774 people died, according to the World Health Organization.
MERS is even more deadly, claiming about 30 percent of people it infects. Unlike SARS, outbreaks of that virus are still simmering, Fauci says. Since 2012, MERS has caused 2,494 confirmed cases in 27 countries and killed 858 people.
MERS can spread from person to person, and some “superspreaders” have passed the virus on to many others. Most famously, 186 people contracted MERS after one businessman unwittingly brought the virus to South Korea in 2015 and spread it to others. Another superspreader who caught MERS from that man passed the virus to 82 people over just two days while being treated in a hospital emergency room (SN: 7/8/16).
Right now, 2019-nCoV appears to be less virulent, with about a 4 percent mortality rate. But that number is still a moving target as more cases are diagnosed, Fauci says. As of January 23, the new coronavirus had infected more than 581 people, with about a quarter of those becoming seriously ill, according to the WHO. By January 24, the number of reported infections had risen to at least 900.