Loading ...Silver is good with Vanco given in low doses though it says. So what’s low doses I have to find out.
How it works with Vancomycin. It’s synergistic not additive and enhances the effect by breaking down the barrier of the bacteria that could be resistant to vanco. But I still have to find out what the other one they added. It’s seems it would be a good mixture of vanco and silver nano particles infiltrated cement would be excellent to go on the infected bone especially if adding hardware.
…Low doses of silver can make vancomycin more effective against Gram-negative bacteria, which are often resistant to larger antibiotics like vancomycin.
This is how it works.
…Silver works by making bacteria produce more reactive oxygen species (ROS) and by making the cell membrane more permeable. This allows more antibiotics to enter the bacterial cells, which can overwhelm the bacteria’s resistance mechanisms.